PC-766B Catalog No.:M22658-C CAS Number: 90-15-3

CAS Number: 90-15-3

CAS Number: 484-29-7

while 14-fold higher concentrations are required in rat plasma (IC50 290 nM)

tail vein and topical injection) inhibits the growth of PC-3M tumors in mice

W-7 antagonizes the smooth muscle contraction through the inhibition of the initial increase in the P-LC phosphorylation

PC-766B Catalog No.:M22658-C CAS Number: 90-15-3PC 766B is a macrolide antibiotic existed in anactinomycete strain SC 4710. PC 766B was active against Gram positive bacteria, and some fungi and yeasts, yet inactive against Gram negative bacteria. PC 766B exhibited potent cytotoxicity against murine tumor cell lines in vitro. The IC50 values against P388 leukemia and B16 melanoma were 0. 1 and 0. 5 ng ml, respectively . Intraperitoneal administration of PC 766B (0. 25mg kg day) showed in vivo